Baltimore, Maryland, May 19, 2011
– CompuCyte
Corporation today announced the introduction of a live-cell
analysis option for its iGeneration family of high-content
imaging cytometry instrumentation.
The new option will allow researchers to perform
time-lapse studies and high-content quantitative analysis of
living cells.
The announcement was made at CYTO 2011, the 26th
Congress of the International Society for Advancement of
Cytometry, currently being held in Baltimore.
The Live Cell Analysis option integrates a stage-top
environmental control chamber manufactured by Tokai Hit
Company, Ltd. (Tokyo, Japan) into the iGeneration analysis
workflow. The
Tokai Hit incubator allows cells to survive for several
days, opening the opportunity for longer-term kinetic
studies.
“The addition of live-cell analysis capabilities is a
significant advance for CompuCyte’s laser scanning cytometry
technology,” stated Mel Henriksen, CompuCyte’s Vice
President of Research and Development.
“CompuCyte has long been recognized as a major
provider of imaging cytometry instrumentation for adherent
cells and tissue specimens.
The new environmental control capability will meet
the demand for longer-term live-cell analyses on LSC
systems. Most
importantly, the live-cell analysis option opens the door to
high-content analysis protocols that are not available with
other cytometry technologies. Living cells can be analyzed
using live-cell stains and then fixed, treated further, and
reanalyzed with stains that measure other characteristics --
for example, membrane permeability, or markers of DNA
damage, apoptosis, or senescence.
The results of the two cytometric runs can then be
combined into a single data set, allowing a comprehensive,
multiplexed data analysis utilizing data elements generated
from each of the separate runs.
By combining this capacity for live- and fixed-cell
analysis with CompuCyte’s patented technique for merging
data obtained from multiple runs of the same specimen,
researchers can take advantage of CompuCyte’s unique
analysis capabilities in ways that have not been possible
before.”
CompuCyte Corporation, a privately held corporation
headquartered in Westwood, Massachusetts, is a pioneer in
the field of quantitative imaging cytometry (QIC).
The company’s comprehensive line of laser scanning
cytometry instrumentation is applied to automated cellular
and tissue analysis in life science research, drug safety,
toxicology studies and clinical trials.
Committed to educational programs and promotion of
the science and practice of LSC technology, CompuCyte
actively maintains the International QIC Centers of
Excellence program (www.imagingcytometrycenter.com) and the
annual International QIC Symposium.
More information about CompuCyte Corporation and its
technology may be found at
www.compucyte.com.
